Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.46 |
| ▸ | F2 | P00734 | 8/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6165502 | 0.87 | ALOX5 (0.41) | F10PRSS1F2ALOX5PRSS2 | |
| Trifluoroacetic Acid SCHEMBL6163584 | 0.87 | F10 (0.46) | F10PRSS1F2ALOX5PRSS2 | |
| Trifluoroacetic Acid SCHEMBL6166404 | 0.83 | PRSS1 (0.53) | F10PRSS1F2PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL6165958 | 0.82 | PRSS1 (0.46) | F10PRSS1F2PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL6167982 | 0.82 | F10 (0.42) | F10PRSS1F2ALOX5PRSS2 | |
| Trifluoroacetic Acid SCHEMBL6161730 | 0.81 | MAPT (0.49) | F10PRSS1F2ALOX5PRSS2 | |
| Trifluoroacetic Acid SCHEMBL6166475 | 0.80 | SMN1; SMN2 (0.53) | F10PRSS1F2ALOX5PRSS2 | |
| Trifluoroacetic Acid SCHEMBL6165291 | 0.79 | F10 (0.45) | F10PRSS1F2CDC7DBF4 | |
| SCHEMBL6166441 | 0.79 | MMP2 (0.42) | ALOX5MMP2MMP13MMP14 | |
| Trifluoroacetic Acid SCHEMBL6162234 | 0.78 | SMN1; SMN2 (0.48) | F10PRSS1F2ALOX5PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | claimed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | claimed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | claimed |