Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950507 | 1.00 | HDAC3 (0.43) | HDAC3HSD17B3NOTUMMAOAMAOB | |
| Hydrochloric Acid SCHEMBL7007436 | 0.98 | HDAC3 (0.43) | HDAC3HSD17B3NOTUMMAOAMAOB | |
| Tetrahydrofuran SCHEMBL28323243 | 0.89 | HDAC3 (0.40) | HDAC3HSD17B3MAOAMAOBKDM4E | |
| SCHEMBL15323808 | 0.88 | HSD17B3 (0.40) | HDAC3HSD17B3NOTUMMAOAMAOB | |
| SCHEMBL27872842 | 0.85 | HDAC3 (0.43) | HDAC3HSD17B3NOTUMMAOAMAOB | |
| SCHEMBL4552418 | 0.84 | P2RX4 (0.45) | HDAC3HSD17B3SMN1; SMN2ALDH1A1AKR1C3 | |
| SCHEMBL305168 | 0.84 | HDAC3 (0.43) | HDAC3HSD17B3NOTUMMAOAKDM4E | |
| SCHEMBL30014867 | 0.84 | HDAC3 (0.43) | HDAC3HSD17B3NOTUMMAOAMAOB | |
| SCHEMBL29493257 | 0.84 | HDAC3 (0.43) | HDAC3HSD17B3NOTUMMAOAKDM4E | |
| SCHEMBL6168375 | 0.84 | HSD17B3 (0.49) | HDAC3HSD17B3NOTUMP2RX4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752492-A1 | FUNGICIDAL OXADIAZOLES | Bayer Aktiengesellschaft (DE) | 2020-12-23 | — | — | EP | claimed |
| CN-111836802-A | Fungicidal acibenzoates | 拜耳公司 | 2020-10-27 | — | — | CN | claimed |
| WO-2019155066-A1 | FUNGICIDAL OXADIAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 2019-08-15 | — | — | WO | claimed |
| CN-102395273-B | Thienopyridine derivatives for the treatment and prevention of dengue virus infection | SIGA TECHNOLOGIES INC | 2015-05-20 | — | — | CN | claimed |
| WO-2013041407-A1 | HYDROXAMIC ACIDS AS HDAC6 INHIBITORS | CELLZOME AG (DE) | 2013-03-28 | — | — | WO | claimed |
| CN-102395273-A | Thienopyridine derivatives for the treatment and prevention of dengue virus infection | SIGA TECHNOLOGIES INC | 2012-03-28 | — | — | CN | claimed |
| JP-2012500853-A | — | — | 2012-01-12 | — | — | JP | claimed |
| EP-2328871-A2 | HEDGEHOG PATHWAY MODULATORS | IRM LLC (BM) | 2011-06-08 | — | — | EP | claimed |
| WO-2010099166-A1 | THIENOPYRIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DENGUE VIRUS INFECTIONS | SIGA TECHNOLOGIES, INC. (US) | 2010-09-02 | — | — | WO | claimed |
| WO-2010027746-A2 | HEDGEHOG PATHWAY MODULATORS | IRM LLC (BM) | 2010-03-11 | — | — | WO | claimed |
| US-4013468-A | Method of hardening a protein-containing layer of a silver halide photographic material with an alkyl ester of 1,2-dihydroquinoline-N-carboxylic acid | AGFA-GEVAERT, A.G. (DT) | 1977-03-22 | — | — | US | claimed |
| US-20250387504-A1 | ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF | NOVARTIS AG (CH) | 2025-12-25 | — | — | US | disclosed |
| US-12403137-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2025-09-02 | — | — | US | disclosed |
| WO-2024227104-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BRAF VIA UBIQUITIN PROTEOSOME PATHWAY | NURIX THERAPEUTICS, INC. (US) | 2024-10-31 | — | — | WO | disclosed |
| CN-118451079-A | Benzopiperidine derivative modulators, methods of preparation and uses thereof | 上海翰森生物医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |
| US-4069052-A | Color photographic materials with spiro heterocyclic stabilizing agents comprising 2-imidazolidine-4',5'-dione rings | AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) | 1978-01-17 | — | — | US | disclosed |
| US-4059447-A | Photographic material containing oxazolinone-2 couplers | AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) | 1977-11-22 | — | — | US | disclosed |
| US-4052213-A | OXAZOLINONE-2-COMPOUNDS CONTAINING A MERCAPTO GROUP | AGFA-GEVAERT, A.G. (DT) | 1977-10-04 | — | — | US | disclosed |
| US-4046574-A | COLOR PHOTOGRAPHIC MATERIAL WITH HOMOPHTHALIMIDE THIOETHER DEVELOPMENT INHIBITOR | AGFA-GEVAERT, AKTIENGESELLSCHAFT (DT) | 1977-09-06 | — | — | US | disclosed |
| US-3984246-A | MONO-, TRI-, OR PENTAMETHINE OXONOLES OF 1-SULFOLANYL PYRAZOLONES | AGFA-GEVAERT, A.G. (DT) | 1976-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250387504-A1 | ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF | BID, BCL2, MCL1 | HDAC3 951/4885HSD17B3 3666/4885NOTUM 3422/4885 |
| US-12403137-B2 | Compounds and methods of use | XDH, LPXN, F12 | HDAC3 1474/4885HSD17B3 640/4885NOTUM 1224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.