SCHEMBL6169344

SCHEMBL6169344

CCCCOC(=O)N1CCCCC1c1nc(-c2ccc(-c3ccccc3)cc2)c[nH]1

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DAGLA Q9Y4D2 2/20 0.41
CPT1A P50416 10/20 0.41
CPT2 P23786 6/20 0.40
TMEM97 Q5BJF2 2/20 0.40
SIGMAR1 Q99720 2/20 0.40
PRCP P42785 1/20 0.39
CPT1B Q92523 3/20 0.39
P2RY12 Q9H244 3/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6166634 0.91 ALDH1A1 (0.40) CPT1AALDH1A1MAPK1
SCHEMBL17396055 0.88 GCK (0.42) CPT1AALDH1A1MAPK1
SCHEMBL6167867 0.85 CPT1A (0.38) DAGLACPT1ACPT2CPT1BP2RY12
SCHEMBL12600595 0.84 TMEM97 (0.48) DAGLACPT1ACPT2TMEM97SIGMAR1
SCHEMBL1061828 0.84 TMEM97 (0.48) DAGLACPT1ACPT2TMEM97SIGMAR1
SCHEMBL26989028 0.83 NPC1 (0.46) CPT1ACPT2PRCPALDH1A1MAPK1
SCHEMBL6166994 0.82 KDM4E (0.46) P2RY12ALDH1A1
SCHEMBL6167855 0.82 CPT1A (0.43) DAGLACPT1ACPT2CPT1BALDH1A1
SCHEMBL6167984 0.81 P2RY12 (0.44) P2RY12
SCHEMBL23247779 0.81 CPT1A (0.46) DAGLACPT1ACPT2PRCPCPT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1349850-B1 SODIUM CHANNEL MODULATORS DERIVED FROM 2-PIPERIDYLIMIDAZOLES SOD CONSEILS RECH APPLIC (FR) 2005-09-07 EP claimed
US-20040077640-A1 Sodium channel modulators derived from 2-piperidylimidazoles SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 2004-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040077640-A1 Sodium channel modulators derived from 2-piperidylimidazoles KCNH1, HCN4, KCNH2 DAGLA 2629/4885CPT1A 3561/4885CPT2 1578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.