Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804705 | 0.88 | ALDH1A1 (0.48) | CHATKDM4ELMNATSHR | |
| Styrene SCHEMBL138405 | 0.84 | ALDH1A1 (0.56) | CHATPTGS1PTGS2HDAC8HDAC6 | |
| SCHEMBL28690632 | 0.84 | CHAT (0.45) | CHATPTGS1PTGS2HDAC8HDAC6 | |
| SCHEMBL10457001 | 0.83 | CHAT (0.44) | CHATPTGS1PTGS2HDAC8HDAC6 | |
| SCHEMBL10951988 | 0.83 | CHAT (0.44) | CHATPTGS1PTGS2HDAC8HDAC6 | |
| SCHEMBL10558462 | 0.83 | NR1I2 (0.46) | CHATCHRNB4CHRNA3CHRNA7NR1I2 | |
| SCHEMBL14912 | 0.82 | SIRT2 (0.50) | CHATHDAC8HDAC6MTNR1AMTNR1B | |
| SCHEMBL29357296 | 0.82 | SIRT2 (0.50) | CHATHDAC8HDAC6MTNR1AMTNR1B | |
| SCHEMBL31610342 | 0.82 | SIRT2 (0.50) | CHATHDAC8HDAC6MTNR1AMTNR1B | |
| SCHEMBL6863260 | 0.82 | SIRT2 (0.50) | CHATHDAC8HDAC6MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1559713-B1 | Chromene compound | TOKUYAMA CORP (JP) | 2014-09-24 | — | — | EP | disclosed |
| EP-1559713-A1 | Chromene compound | Tokuyama Corporation (JP) | 2005-08-03 | — | — | EP | disclosed |
| EP-1122251-B1 | CHROMENE COMPOUNDS | TOKUYAMA CORP (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-6719926-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2004-04-13 | — | — | US | disclosed |
| US-20030195340-A1 | Chromene compound | MOMODA JUNJI (JP) | 2003-10-16 | — | — | US | disclosed |
| US-6525194-B1 | Naphtho-2,1-b-pyran derivative that develops yellow to red color | TOKUYAMA CORPORATION (JP) | 2003-02-25 | — | — | US | disclosed |
| US-20030028019-A1 | Chromene compound | MOMODA JUNJI (JP) | 2003-02-06 | — | — | US | disclosed |
| US-6469076-B1 | Chromene compounds | TOKUYAMA CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-1122251-A1 | CHROMENE COMPOUNDS | TOKUYAMA CORPORATION (JP) | 2001-08-08 | — | — | EP | disclosed |
| EP-1116723-A1 | CHROMENE COMPOUNDS | TOKUYAMA CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030028019-A1 | Chromene compound | MITF, TYR, CDYL | CHAT 358/4885PTGS1 2727/4885PTGS2 2646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.