Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.43 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6170083 | 0.86 | PPARG (0.47) | PPARGAGTR1AGTR2ACSS2 | |
| SCHEMBL6168473 | 0.85 | ACSS2 (0.55) | PPARGAGTR1AGTR2ACSS2 | |
| SCHEMBL6169652 | 0.82 | PPARG (0.47) | PPARGAGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL7596466 | 0.82 | PPARG (0.54) | PPARGAGTR1AGTR2 | |
| SCHEMBL6168853 | 0.82 | POLB (0.52) | PPARGAGTR1AGTR2ACSS2 | |
| SCHEMBL6169417 | 0.81 | MEN1 (0.53) | PPARGAGTR1AGTR2ACSS2 | |
| SCHEMBL6167804 | 0.81 | PPARG (0.66) | PPARGAGTR1AGTR2 | |
| SCHEMBL6170724 | 0.80 | NAMPT (0.54) | PPARGAGTR1ACSS2 | |
| SCHEMBL6167816 | 0.79 | AGTR1 (0.54) | PPARGAGTR1AGTR2ACSS2 | |
| Hydrochloric Acid SCHEMBL6167898 | 0.79 | PPARG (0.57) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882718-B1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-08-31 | — | — | EP | disclosed |
| US-6352985-B1 | CARDIOVASCULAR DISORDERS OR GASTROINTESTINAL DISORDERS, DIABETES (TYPE II DIABETES), DIABETIC COMPLICATIONS METHOD FOR LOWERING THE BLOOD SUGAR LEVEL OF A PATIENT, | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-05 | — | — | US | disclosed |
| US-6348032-B1 | POTENT COMPOUNDS THAT INDUCE APOPTOSIS IN NEOPLASTIC CELLS (BUT NOT SUBSTANTIALLY IN NORMAL CELLS), WITHOUT SUBSTANTIALLY INHIBITING PGE-2. | CELL PATHWAYS, INC. | 2002-02-19 | — | — | US | disclosed |
| US-6166219-A | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0882718-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |