Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14007696 | 0.84 | RAB9A (0.36) | MEN1KMT2AKDM4EMAPK1PKM | |
| SCHEMBL16963172 | 0.82 | MEN1 (0.46) | MEN1KMT2AKDM4EMAPK1PPARG | |
| SCHEMBL629435 | 0.81 | MEN1 (0.45) | MEN1KMT2AKDM4EMAPK1PPARG | |
| SCHEMBL6169849 | 0.81 | MEN1 (0.53) | MEN1KMT2AKDM4EMAPK1PPARG | |
| SCHEMBL3282837 | 0.77 | PPARG (0.45) | MEN1KMT2AKDM4EMAPK1PPARG | |
| SCHEMBL15082052 | 0.74 | EGLN1 (0.42) | KDM4EPKMPDE10AALDH1A1HCAR2 | |
| SCHEMBL22229724 | 0.72 | PDE10A (0.36) | MAPK1PDE10AALDH1A1HCAR2SMN1; SMN2 | |
| SCHEMBL12758040 | 0.72 | PDE10A (0.38) | KDM4EPKMPDE10AALDH1A1HCAR2 | |
| SCHEMBL1026100 | 0.71 | ALDH1A1 (0.39) | MEN1KMT2AKDM4EMAPK1PKM | |
| Ethane SCHEMBL28790777 | 0.71 | PDE10A (0.39) | KMT2AKDM4EPDE10ATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6914160-B1 | Oxytocin inhibitors | PFIZER INC (US) | 2005-07-05 | — | — | US | disclosed |
| EP-1537085-A1 | OXYTOCIN INHIBITORS | Pfizer Limited (GB) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004020414-A1 | OXYTOCIN INHIBITORS | PFIZER LIMITED (GB) | 2004-03-11 | — | — | WO | disclosed |