Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083033 | 0.74 | MAPT (0.36) | ALDH1A1CYP2D6 | |
| SCHEMBL433182 | 0.70 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL4640870 | 0.67 | — | — | |
| SCHEMBL1078049 | 0.67 | ALDH1A1 (0.57) | ALDH1A1SOAT1 | |
| SCHEMBL8681183 | 0.67 | ALDH1A1 (0.41) | ALDH1A1SOAT1CYP2D6GLA | |
| SCHEMBL8681285 | 0.66 | ALDH1A1 (0.40) | ALDH1A1SOAT1CYP2D6 | |
| SCHEMBL2854656 | 0.65 | ALDH1A1 (0.43) | ALDH1A1SOAT1CYP2D6 | |
| SCHEMBL10344229 | 0.64 | ALDH1A1 (0.52) | ALDH1A1SOAT1 | |
| SCHEMBL2130385 | 0.64 | ALDH1A1 (0.46) | ALDH1A1SOAT1CYP2D6GLA | |
| SCHEMBL305155 | 0.63 | ALDH1A1 (0.50) | ALDH1A1SOAT1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129071-B1 | PHENYL-SUBSTITUTED CYCLIC ENAMINONES | BAYER CROPSCIENCE AG (DE) | 2005-10-26 | — | — | EP | disclosed |
| EP-1129071-A1 | PHENYL-SUBSTITUTED CYCLIC ENAMINONES | Bayer Aktiengesellschaft (DE) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000027812-A1 | PHENYL-SUBSTITUTED CYCLIC ENAMINONES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-05-18 | — | — | WO | disclosed |