Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2074396 | 0.76 | KCNN4 (0.48) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3114470 | 0.73 | HDAC3 (0.45) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1549012 | 0.73 | HDAC3 (0.45) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3249773 | 0.73 | TSHR (0.44) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3246081 | 0.73 | TSHR (0.44) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3665471 | 0.70 | HDAC3 (0.47) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9820206 | 0.69 | KCNN4 (0.50) | KCNN4CYP1A2CYP2D6CA1CA2 | |
| SCHEMBL6379499 | 0.69 | KCNN4 (0.50) | KCNN4CYP1A2CYP2D6CA1CA2 | |
| SCHEMBL9853003 | 0.68 | KCNN4 (0.41) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3249429 | 0.68 | CYP2D6 (0.40) | KCNN4HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000932-B9 | AROMATIC RING DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-0882718-B1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-08-31 | — | — | EP | disclosed |
| EP-1000932-B1 | AROMATIC RING DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6410584-B1 | ANTICANCER AGENTS | CELL PATHWAYS, INC. | 2002-06-25 | — | — | US | disclosed |
| US-6352985-B1 | CARDIOVASCULAR DISORDERS OR GASTROINTESTINAL DISORDERS, DIABETES (TYPE II DIABETES), DIABETIC COMPLICATIONS METHOD FOR LOWERING THE BLOOD SUGAR LEVEL OF A PATIENT, | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-05 | — | — | US | disclosed |
| EP-1132087-A1 | REMEDIES FOR POLYCYSTIC OVARY SYNDROME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-6242474-B1 | SULFONYLCARBAMOYLALKYLIMIDAZOLE DERIVATIVES; ANTIDIABETIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-6166219-A | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-1000932-A1 | AROMATIC RING DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-05-17 | — | — | EP | disclosed |
| EP-0882718-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |