Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 14/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6169297 | 0.94 | NR1H4 (0.43) | NR1H4EPHX2MEN1KMT2AALDH1A1 | |
| SCHEMBL6173478 | 0.88 | F10 (0.47) | NR1H4EPHX2PPARGPPARAF10 | |
| SCHEMBL7089461 | 0.87 | NR1H4 (0.42) | NR1H4EPHX2MEN1KMT2AALDH1A1 | |
| SCHEMBL6170072 | 0.85 | NR1H4 (0.47) | NR1H4EPHX2MEN1KMT2APPARG | |
| SCHEMBL6173466 | 0.84 | NR1H4 (0.58) | NR1H4EPHX2PPARGPPARA | |
| SCHEMBL6171161 | 0.83 | NR1H4 (0.45) | NR1H4EPHX2MEN1KMT2APPARG | |
| SCHEMBL6170547 | 0.82 | MAPT (0.48) | NR1H4EPHX2MEN1KMT2AALDH1A1 | |
| SCHEMBL6168239 | 0.80 | NR1H4 (0.47) | NR1H4EPHX2MEN1KMT2APPARG | |
| SCHEMBL7372132 | 0.79 | NR1H4 (0.43) | NR1H4MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL7083889 | 0.78 | NR1H4 (0.51) | NR1H4EPHX2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019045-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2005-06-08 | — | — | EP | disclosed |
| US-20030078431-A1 | Antithrombotic agents | BEIGHT DOUGLAS WADE (US) | 2003-04-24 | — | — | US | disclosed |
| US-6500851-B2 | ANTICOAGULANT IN MAMMLS | ELI LILLY AND COMPANY | 2002-12-31 | — | — | US | disclosed |
| US-20020173518-A1 | Antithrombotic agents | BEIGHT DOUGLAS WADE (US) | 2002-11-21 | — | — | US | disclosed |
| US-6372759-B1 | BLOOD COAGULATION FACTOR XA FOR MAMMALS | ELI LILLY AND COMPANY | 2002-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173518-A1 | Antithrombotic agents | SERPINC1, TFPI, F11 | NR1H4 1884/4885EPHX2 445/4885MEN1 1304/4885 |
| US-20030078431-A1 | Antithrombotic agents | SERPINC1, TFPI, F11 | NR1H4 1884/4885EPHX2 445/4885MEN1 1304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.