Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL10920606 | 0.98 | TSHR (0.34) | TSHRSMN1; SMN2MAPTKDM4CKMT2A | |
| SCHEMBL8593888 | 0.82 | TSHR (0.35) | TSHRSMN1; SMN2MAPTKMT2AFAAH | |
| SCHEMBL2850386 | 0.80 | TSHR (0.37) | TSHRSMN1; SMN2MAPTKMT2AFAAH | |
| SCHEMBL5954434 | 0.78 | PKM (0.35) | TSHRSMN1; SMN2MAPTKMT2AFAAH | |
| SCHEMBL438355 | 0.78 | TSHR (0.39) | TSHRSMN1; SMN2MAPTKMT2AFAAH | |
| SCHEMBL11663791 | 0.77 | MAPK1 (0.36) | TSHRSMN1; SMN2MAPTKMT2AFAAH | |
| Hydrochloric Acid SCHEMBL10962377 | 0.77 | PKM (0.34) | TSHRSMN1; SMN2MAPTKMT2AFAAH | |
| SCHEMBL11564414 | 0.76 | KDM4C (0.34) | TSHRKDM4CALDH1A1CYP2C19CYP2D6 | |
| SCHEMBL7600761 | 0.75 | KMT2A (0.33) | TSHRSMN1; SMN2MAPTKMT2AFAAH | |
| SCHEMBL10719108 | 0.70 | TSHR (0.42) | TSHRMAPTKDM4CALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12404299-B2 | Method for producing peptide compound comprising highly sterically hindered amino acid | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2025-09-02 | — | — | US | disclosed |
| CN-114630835-B | Process for the preparation of peptide compounds comprising sterically bulky amino acids | 中外制药株式会社 | 2025-02-11 | — | — | CN | disclosed |
| US-20230026641-A1 | METHOD FOR PRODUCING PEPTIDE COMPOUND COMPRISING HIGHLY STERICALLY HINDERED AMINO ACID | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-01-26 | — | — | US | disclosed |
| US-20230026641-A1 | METHOD FOR PRODUCING PEPTIDE COMPOUND COMPRISING HIGHLY STERICALLY HINDERED AMINO ACID | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-01-26 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-4056580-A1 | METHOD FOR PRODUCING PEPTIDE COMPOUND COMPRISING HIGHLY STERICALLY HINDERED AMINO ACID | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-09-14 | — | — | EP | disclosed |
| EP-1546111-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004031160-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-04-15 | — | — | WO | disclosed |
| US-5773485-A | CURABLE MONOMERS FOR ACRYLATE POLYMERS FOR COATINGS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-06-30 | — | — | US | disclosed |
| WO-1998023713-A1 | WATERLESS AND SOLVENT HAND AND SKIN CLEANER | HAISTEN EUGENE KEITH JR (US) | 1998-06-04 | — | — | WO | disclosed |
| EP-0106266-B1 | TERPENE-SOLVENT MIXTURE USEFUL FOR MAKING LIQUID DETERGENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1988-02-24 | — | — | EP | disclosed |
| EP-0105063-B1 | LIQUID HARD-SURFACE CLEANER | THE PROCTER & GAMBLE COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |
| EP-0040882-B1 | LIQUID DETERGENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1985-01-30 | — | — | EP | disclosed |
| EP-0106266-A2 | Terpene-solvent mixture useful for making liquid detergent compositions | THE PROCTER & GAMBLE COMPANY (US) | 1984-04-25 | — | — | EP | disclosed |
| EP-0105063-A1 | Liquid hard-surface cleaner | THE PROCTER & GAMBLE COMPANY (US) | 1984-04-11 | — | — | EP | disclosed |
| US-4414128-A | SURFACTANT, A TERPENE, OXY SOLVENT | THE PROCTER & GAMBLE COMPANY (US) | 1983-11-08 | — | — | US | disclosed |
| EP-0040882-A1 | Liquid detergent compositions | THE PROCTER & GAMBLE COMPANY (US) | 1981-12-02 | — | — | EP | disclosed |
| US-4082792-A | SECONDARY ALKYL PRIMARY AMINE, ALKENOIC ACID, PRIMARY OR SECONDARY ALCOHOL | TEXACO INC. (US) | 1978-04-04 | — | — | US | disclosed |
| US-3976682-A | ALKYLAMMONIUM ALKYLAMINOALKANOATES, FREEZE-THAW ADDITIVE, CORROSION INHIBITOR, PIGMENT GRINDING | TEXACO INC. (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026641-A1 | METHOD FOR PRODUCING PEPTIDE COMPOUND COMPRISING HIGHLY STERICALLY HINDERED AMINO ACID | DNPEP, VIP, NPEPPS | TSHR 1360/4885SMN1; SMN2 2268/4885MAPT 2810/4885 |
| US-12404299-B2 | Method for producing peptide compound comprising highly sterically hindered amino acid | DNPEP, VIP, NPEPPS | TSHR 1360/4885SMN1; SMN2 2268/4885MAPT 2810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.