Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LDHA | P00338 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 2/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29360190 | 0.83 | KMT2A (0.49) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL2116138 | 0.82 | KMT2A (0.59) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL2432852 | 0.82 | RAB9A (0.56) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL11863320 | 0.82 | LOXL2 (0.57) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL9010390 | 0.82 | DAO (0.68) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL2116925 | 0.82 | RAB9A (0.75) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL1584925 | 0.82 | RAB9A (0.56) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL9010386 | 0.78 | MEN1 (0.50) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL9144054 | 0.77 | NPC1 (0.51) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL2119743 | 0.76 | NPC1 (0.53) | RAB9ANPC1CYP1A2CYP2C19RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1495020-A1 | N-(MORPHOLIN-2YL) METHYL ACETAMIDE DERIVATIVES AS CCR-3 ANTAGONISTS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003082863-A1 | N-(MORPHOLIN-2YL) METHYL ACETAMIDE DERIVATIVES AS CCR-3 ANTAGONISTS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2003-10-09 | — | — | WO | disclosed |