Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168823 | 0.79 | CYP2D6 (0.33) | HTTNPSR1ALDH1A1KMT2AKDM4E | |
| SCHEMBL6168559 | 0.79 | KDM4E (0.31) | ALDH1A1KDM4EMAPTTDP1L3MBTL1 | |
| SCHEMBL2861141 | 0.78 | CYP2D6 (0.42) | HTTNPSR1ALDH1A1KMT2AKDM4E | |
| SCHEMBL6167566 | 0.75 | SMN1; SMN2 (0.42) | HTTNPSR1ALDH1A1KMT2AKDM4E | |
| SCHEMBL6210539 | 0.73 | SMN1; SMN2 (0.32) | HTTNPSR1ALDH1A1KMT2AKDM4E | |
| SCHEMBL9183270 | 0.73 | ALDH1A1 (0.44) | HTTNPSR1ALDH1A1KMT2AKDM4E | |
| SCHEMBL890760 | 0.73 | NOS3 (0.35) | HTTNPSR1ALDH1A1KMT2AKDM4E | |
| SCHEMBL28205435 | 0.68 | CYP2D6 (0.40) | HTTNPSR1ALDH1A1KMT2AKDM4E | |
| SCHEMBL2702055 | 0.67 | ALDH1A1 (0.43) | HTTNPSR1ALDH1A1KMT2AKDM4E | |
| SCHEMBL8802907 | 0.66 | CYP2D6 (0.33) | HTTNPSR1ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1498109-A1 | Furan derivatives and dyeing composition comprising a furan derivative as coupler | L'OREAL (FR) | 2005-01-19 | — | — | EP | claimed |
| EP-1498109-A1 | Furan derivatives and dyeing composition comprising a furan derivative as coupler | L'OREAL (FR) | 2005-01-19 | — | — | EP | disclosed |