Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6171470 | 0.80 | CYP4F2 (0.54) | CYP4F2CYP4A11RAB9ANPC1MAPT | |
| SCHEMBL7669344 | 0.78 | ADA (0.50) | CYP4F2CYP4A11F2F10 | |
| SCHEMBL6168436 | 0.78 | SLC7A5 (0.44) | CYP4F2CYP4A11ADRB2ADRB1ADRB3 | |
| SCHEMBL6171832 | 0.77 | DHFR (0.41) | ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL6171825 | 0.77 | DHFR (0.41) | ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL6990853 | 0.76 | HDAC3 (0.42) | ADRB2ADRB1ADRB3MAPTSMN1; SMN2 | |
| SCHEMBL6990850 | 0.76 | HDAC3 (0.42) | ADRB2ADRB1ADRB3MAPTSMN1; SMN2 | |
| SCHEMBL20261156 | 0.76 | ADRB2 (0.53) | ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL29235353 | 0.76 | ADRB2 (0.53) | ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL6990188 | 0.75 | HDAC3 (0.36) | ADRB2ADRB1ADRB3RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098885-B9 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-05-18 | — | — | EP | disclosed |
| EP-1098885-B1 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-11-17 | — | — | EP | disclosed |
| US-6359145-B1 | ADENOSINE DEAMINASE INHIBITOR; ANTIINFLAMMATORY AGENTS; IMMUNOSUPPRESSANT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |