SCHEMBL6171237

SCHEMBL6171237

CCOC(=O)c1ccc(NC(=O)CC)c(N)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 3/20 0.62
ALOX15 P16050 1/20 0.60
GAA P10253 3/20 0.53
RAB9A P51151 4/20 0.52
NPC1 O15118 3/20 0.52
LMNA P02545 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
MAOA P21397 1/20 0.51
KMT2A Q03164 2/20 0.49
ERAP2 Q6P179 1/20 0.49
LNPEP Q9UIQ6 1/20 0.49
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA7 P43166 1/20 0.49
CA9 Q16790 1/20 0.49
CA14 Q9ULX7 1/20 0.49
ALDH1A1 P00352 4/20 0.47
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6169580 0.87 PTGER4 (0.64) PTGER4ALOX15GAARAB9ANPC1
SCHEMBL408918 0.84 PTGER4 (0.67) PTGER4ALOX15GAARAB9ANPC1
SCHEMBL8889095 0.83 PTGER4 (0.60) PTGER4ALOX15GAARAB9ANPC1
SCHEMBL14800323 0.82 PTGER4 (0.73) PTGER4ALOX15GAARAB9ANPC1
SCHEMBL11252923 0.82 PTGER4 (0.58) PTGER4ALOX15GAARAB9ANPC1
SCHEMBL753526 0.81 PTGER4 (0.57) PTGER4ALOX15GAALMNACYP1A2
SCHEMBL4341372 0.80 ALOX15 (0.63) PTGER4ALOX15GAARAB9ANPC1
SCHEMBL8887638 0.79 PTGER4 (0.64) PTGER4ALOX15GAARAB9ANPC1
SCHEMBL16846282 0.79 PTGER4 (0.76) PTGER4ALOX15GAARAB9ANPC1
SCHEMBL10970214 0.79 L3MBTL1 (0.55) RAB9ANPC1LMNACYP1A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170281782-A1 CARBOSILANE DENDRIMER AND AGGREGATABLE CARRIER OBTAINED USING SAID DENDRIMER FOR DRUG DELIVERY SYSTEM Cysay Inc. (JP) 2017-10-05 US disclosed
EP-0882718-B1 BENZIMIDAZOLE DERIVATIVES FUJISAWA PHARMACEUTICAL CO (JP) 2005-08-31 EP disclosed
US-6352985-B1 CARDIOVASCULAR DISORDERS OR GASTROINTESTINAL DISORDERS, DIABETES (TYPE II DIABETES), DIABETIC COMPLICATIONS METHOD FOR LOWERING THE BLOOD SUGAR LEVEL OF A PATIENT, FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-03-05 US disclosed
US-6166219-A Benzimidazole derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-12-26 US disclosed
CN-1211238-A Benzimidazole derivatives FUJISAWA PHARMACEUTICAL CO (JP) 1999-03-17 CN disclosed
EP-0882718-A1 BENZIMIDAZOLE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-12-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170281782-A1 CARBOSILANE DENDRIMER AND AGGREGATABLE CARRIER OBTAINED USING SAID DENDRIMER FOR DRUG DELIVERY SYSTEM CTTN, CD44, SCAMP2 PTGER4 3031/4885ALOX15 4394/4885GAA 2553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.