Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 7/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1362893 | 0.83 | FPR2 (0.46) | ALDH1A1FPR2MMP1MMP3MMP7 | |
| SCHEMBL23890513 | 0.79 | ADRA2A (0.45) | ALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL6267722 | 0.78 | KMT2A (0.55) | ALDH1A1GAAKMT2ATSHRFPR2 | |
| SCHEMBL27693248 | 0.78 | FPR2 (0.44) | ALDH1A1FPR2MMP1MMP3MMP7 | |
| SCHEMBL6448258 | 0.77 | FPR2 (0.43) | ALDH1A1FPR2MMP1MMP3MMP7 | |
| SCHEMBL28626525 | 0.77 | FPR2 (0.43) | ALDH1A1FPR2MMP1MMP3MMP7 | |
| SCHEMBL570524 | 0.77 | ADRA2A (0.47) | ALDH1A1FPR2MMP1MMP3MMP7 | |
| SCHEMBL5460567 | 0.75 | CSNK1A1 (0.44) | ALDH1A1FPR2MMP1MMP3MMP7 | |
| Bromide SCHEMBL28219788 | 0.75 | ADRA2A (0.46) | ALDH1A1FPR2MMP1MMP3MMP7 | |
| Hydrochloric Acid SCHEMBL28220351 | 0.75 | ADRA2A (0.46) | ALDH1A1FPR2MMP1MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966446-B1 | BICYCLIC INHIBITORS OF PROTEIN FARNESYL TRANSFERASE | WARNER LAMBERT CO (US) | 2005-10-19 | — | — | EP | disclosed |
| EP-0861245-A1 | PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES | MERCK SHARP & DOHME LTD. (GB) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997019073-A1 | PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1997-05-29 | — | — | WO | disclosed |
| CN-1033995-A | 4 (5)-imidazoles that suppress aromatase enzyme | FARMOS OY (FI) | 1989-07-19 | — | — | CN | disclosed |