Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UNG | P13051 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6172243 | 0.84 | MEN1 (0.38) | MEN1KMT2AMRGPRX4RXRARXRB | |
| SCHEMBL21817202 | 0.83 | MRGPRX4 (0.38) | MEN1KMT2AMRGPRX4RXRARXRB | |
| SCHEMBL6173331 | 0.83 | PTGS2 (0.55) | PTGS2 | |
| SCHEMBL6173335 | 0.83 | PTGS2 (0.55) | PTGS2 | |
| SCHEMBL6170674 | 0.82 | HIF1A (0.44) | MEN1KMT2AMRGPRX4ALDH1A1KDM4E | |
| SCHEMBL8018718 | 0.81 | MAOA (0.47) | UNGALDH1A1KDM4E | |
| SCHEMBL9342265 | 0.79 | RXRA (0.51) | ALDH1A1RXRARXRBRXRGNR4A1 | |
| SCHEMBL304400 | 0.79 | PPARG (0.39) | ALDH1A1KDM4E | |
| SCHEMBL21817599 | 0.79 | MRGPRX4 (0.35) | MEN1KMT2AMRGPRX4ALDH1A1 | |
| SCHEMBL7451099 | 0.78 | UNG (0.36) | UNGMEN1KMT2AMRGPRX4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192127-B1 | SUBSTITUTED BENZAMIDE INHIBITORS OF RHINOVIRUS 3C PROTEASE | AGOURON PHARMA (US) | 2005-03-30 | — | — | EP | disclosed |
| US-6369226-B1 | ENZYME INHIBITORS | AGOURON PHARMACEUTICALS, INC. | 2002-04-09 | — | — | US | disclosed |