Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.49 |
| ▸ | BCHE | P06276 | 5/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6173327 | 0.87 | HTR1A (0.49) | ABCB1BCHEABCG2HTR1ADRD2 | |
| SCHEMBL6173226 | 0.85 | RCE1 (0.48) | BCHERCE1KCNH2KDM4ELMNA | |
| SCHEMBL6171131 | 0.83 | RCE1 (0.42) | BCHERCE1TAAR1LMNAHTT | |
| SCHEMBL6173227 | 0.82 | SLC6A2 (0.49) | RCE1TAAR1LMNAHTT | |
| SCHEMBL6170668 | 0.82 | PTGES (0.43) | HTR1ADRD2 | |
| SCHEMBL6170362 | 0.80 | KMT2A (0.46) | RCE1KDM4EKMT2ASIGMAR1 | |
| SCHEMBL6172965 | 0.80 | RCE1 (0.42) | BCHERCE1HTTKMT2AL3MBTL1 | |
| SCHEMBL6173917 | 0.80 | KMT2A (0.46) | RCE1KDM4EKMT2ASIGMAR1 | |
| SCHEMBL6134190 | 0.80 | RCE1 (0.40) | BCHERCE1KCNH2LMNAHTT | |
| SCHEMBL6173727 | 0.80 | KMT2A (0.46) | RCE1KDM4EKMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098885-B9 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-05-18 | — | — | EP | disclosed |
| EP-1098885-B1 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-11-17 | — | — | EP | disclosed |
| US-6359145-B1 | ADENOSINE DEAMINASE INHIBITOR; ANTIINFLAMMATORY AGENTS; IMMUNOSUPPRESSANT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-1098885-A1 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000005217-A1 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-02-03 | — | — | WO | disclosed |