Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 18/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6173179 | 0.86 | IGF1R (0.49) | IGF1RXIAPBIRC2 | |
| SCHEMBL6171982 | 0.77 | IGF1R (0.41) | IGF1R | |
| SCHEMBL6174468 | 0.74 | IGF1R (0.40) | IGF1R | |
| SCHEMBL2941287 | 0.74 | IGF1R (0.49) | IGF1R | |
| SCHEMBL6173451 | 0.72 | IGF1R (0.41) | IGF1RXIAPBIRC2 | |
| SCHEMBL6175552 | 0.71 | IGF1R (0.38) | IGF1R | |
| SCHEMBL6173810 | 0.68 | MAPT (0.35) | — | |
| SCHEMBL6173911 | 0.66 | IGF1R (0.42) | IGF1R | |
| SCHEMBL2935234 | 0.66 | IGF1R (0.48) | IGF1R | |
| SCHEMBL2938509 | 0.66 | SMO (0.52) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |