Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5178231 | 0.96 | L3MBTL1 (0.38) | PLA2G2AL3MBTL1ATMTDP1MEN1 | |
| SCHEMBL8978512 | 0.91 | ATM (0.41) | L3MBTL1ATMTDP1MEN1KMT2A | |
| SCHEMBL5101722 | 0.90 | KDM4E (0.36) | L3MBTL1TDP1MEN1KMT2AKDM4E | |
| SCHEMBL5094512 | 0.89 | AKR1C3 (0.39) | PLA2G2AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5107921 | 0.88 | L3MBTL1 (0.40) | PLA2G2AL3MBTL1ATMTDP1MEN1 | |
| SCHEMBL1331988 | 0.88 | MAPT (0.36) | PLA2G2AL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL30914186 | 0.88 | MAPT (0.36) | PLA2G2AL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL10102254 | 0.88 | ATM (0.39) | L3MBTL1ATMTDP1MEN1KMT2A | |
| SCHEMBL5107968 | 0.87 | MAPK8 (0.41) | PLA2G2AL3MBTL1ATMTDP1MEN1 | |
| SCHEMBL6132018 | 0.87 | L3MBTL1 (0.41) | L3MBTL1ATMTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112263-B1 | POLYMERIZABLE POLYALKOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2005-06-08 | — | — | EP | disclosed |
| US-6113814-A | PHOTOCHROMIC; END-CAPPED WITH A POLYMERIZABLE GROUP. | TRANSITIONS OPTICAL, INC. (US) | 2000-09-05 | — | — | US | disclosed |