Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA11 | O75493 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12894237 | 0.81 | PIK3CG (0.54) | PIK3CGPIK3CDPIK3CAPIK3CBDYRK1A | |
| SCHEMBL24624393 | 0.79 | PIK3CD (0.46) | CLK1PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL25865065 | 0.79 | DYRK1A (0.44) | PIK3CGPIK3CDPIK3CAPIK3CBDYRK1A | |
| SCHEMBL1841799 | 0.78 | L3MBTL1 (0.46) | CLK1PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL25865064 | 0.77 | ALDH1A1 (0.43) | PIK3CGPIK3CDPIK3CAPIK3CBDYRK1A | |
| SCHEMBL25865063 | 0.77 | ALDH1A1 (0.43) | PIK3CGPIK3CDPIK3CAPIK3CBDYRK1A | |
| SCHEMBL1845956 | 0.76 | PIK3CA (0.45) | PIK3CGPIK3CDPIK3CAPIK3CBDYRK1A | |
| SCHEMBL25865060 | 0.76 | DYRK1A (0.45) | PIK3CGPIK3CDPIK3CAPIK3CBDYRK1A | |
| SCHEMBL14288340 | 0.74 | PIK3CG (0.47) | PIK3CGPIK3CDPIK3CAPIK3CBDYRK1A | |
| SCHEMBL27459155 | 0.71 | DYRK1A (0.43) | PIK3CGPIK3CDPIK3CAPIK3CBDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124810-B9 | 2-AMINO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA ITALIA SPA (IT) | 2005-12-28 | — | — | EP | claimed |
| EP-1124810-B1 | 2-AMINO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA ITALIA SPA (IT) | 2005-05-04 | — | — | EP | claimed |