Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 3/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 14/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 14/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL6174305 | 0.89 | F2 (0.52) | ESR1ESR2F2ALDH1A1 | |
| SCHEMBL6171170 | 0.89 | ESR1 (0.59) | ESR1ESR2F2ALDH1A1 | |
| SCHEMBL6173290 | 0.87 | ESR1 (0.52) | ESR1ESR2F2 | |
| SCHEMBL6598702 | 0.86 | ESR1 (0.58) | ESR1ESR2F2ALDH1A1 | |
| SCHEMBL6597513 | 0.86 | ESR1 (0.59) | ESR1ESR2F2 | |
| SCHEMBL6592408 | 0.86 | ESR1 (0.65) | ESR1ESR2F2ALDH1A1 | |
| SCHEMBL6594992 | 0.86 | ESR1 (0.55) | ESR1ESR2F2 | |
| SCHEMBL6174247 | 0.85 | F2 (0.57) | ESR1ESR2F2 | |
| SCHEMBL6173218 | 0.84 | ESR1 (0.49) | ESR1ESR2F2 | |
| SCHEMBL6599474 | 0.82 | ESR1 (0.55) | ESR1ESR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027051-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2005-01-05 | — | — | EP | disclosed |
| US-6391901-B1 | Thrombin inhibitors | ELI LILLY AND COMPANY | 2002-05-21 | — | — | US | disclosed |