Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.73 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.50 |
| ▸ | PRKDC | P78527 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6179898 | 0.91 | CYSLTR1 (0.73) | CYSLTR1CYP1A1CYP1A2CYP1B1PRKDC | |
| SCHEMBL6175024 | 0.90 | CYSLTR1 (0.71) | CYSLTR1CYP1A1CYP1A2CYP1B1SLC16A3 | |
| SCHEMBL6176722 | 0.88 | CYSLTR1 (0.57) | CYSLTR1CYP1A1CYP1A2CYP1B1L3MBTL1 | |
| SCHEMBL24533170 | 0.86 | CYSLTR1 (0.73) | CYSLTR1CYP1A1CYP1A2CYP1B1ABCB1 | |
| SCHEMBL6176125 | 0.83 | CYSLTR1 (1.00) | CYSLTR1 | |
| SCHEMBL1516397 | 0.83 | CYSLTR1 (0.78) | CYSLTR1CYP1A1CYP1A2CYP1B1PRKDC | |
| SCHEMBL10994445 | 0.82 | CYSLTR1 (0.78) | CYSLTR1CYP1A1CYP1A2CYP1B1ABCB1 | |
| SCHEMBL6177588 | 0.82 | CYSLTR1 (1.00) | CYSLTR1CYP1A1CYP1A2CYP1B1ABCB1 | |
| Hydrochloric Acid SCHEMBL10995142 | 0.82 | CYSLTR1 (0.76) | CYSLTR1CYP1A1CYP1A2CYP1B1PRKDC | |
| Hydrochloric Acid SCHEMBL10987922 | 0.81 | CYSLTR1 (0.76) | CYSLTR1CYP1A1CYP1A2CYP1B1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834510-B1 | Flavone derivative and medicine comprising the same | KOWA CO (JP) | 2005-02-23 | — | — | EP | disclosed |
| US-6136848-A | ANTIALLERGENS; ASTHMA THERAPY | KOWA CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0834510-A2 | Flavone derivative and medicine comprising the same | KOWA CO. LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |