Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | TNKS | O95271 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177306 | 0.91 | CYSLTR1 (0.57) | CYSLTR1MAOBTNKSKDM4EPPARG | |
| SCHEMBL6176117 | 0.91 | CYSLTR1 (0.58) | CYSLTR1MAOBCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL6174522 | 0.88 | CYSLTR1 (0.73) | CYSLTR1CYP1A1CYP1A2CYP1B1L3MBTL1 | |
| SCHEMBL8874138 | 0.88 | CYSLTR1 (0.59) | CYSLTR1MAOBCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL6177041 | 0.85 | TNKS (0.57) | CYSLTR1MAOBCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL6175634 | 0.84 | CYSLTR1 (0.79) | CYSLTR1 | |
| SCHEMBL6178507 | 0.83 | CYSLTR1 (0.52) | CYSLTR1MAOBCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL6178502 | 0.83 | CYSLTR1 (0.80) | CYSLTR1MAOBCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL24533170 | 0.81 | CYSLTR1 (0.73) | CYSLTR1CYP1A1CYP1A2CYP1B1TNKS | |
| SCHEMBL6177248 | 0.80 | TNKS (0.66) | MAOBCYP1A1CYP1A2CYP1B1TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834510-B1 | Flavone derivative and medicine comprising the same | KOWA CO (JP) | 2005-02-23 | — | — | EP | disclosed |
| US-6136848-A | ANTIALLERGENS; ASTHMA THERAPY | KOWA CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0834510-A2 | Flavone derivative and medicine comprising the same | KOWA CO. LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |