Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.73 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174522 | 0.91 | CYSLTR1 (0.73) | CYSLTR1CYP1A1CYP1B1CYP1A2ABCB1 | |
| SCHEMBL6176117 | 0.88 | CYSLTR1 (0.58) | CYSLTR1CYP1A1CYP1B1CYP1A2ABCB1 | |
| SCHEMBL6176125 | 0.85 | CYSLTR1 (1.00) | CYSLTR1 | |
| SCHEMBL6177588 | 0.82 | CYSLTR1 (1.00) | CYSLTR1CYP1A1CYP1B1CYP1A2ABCB1 | |
| SCHEMBL24533170 | 0.82 | CYSLTR1 (0.73) | CYSLTR1CYP1A1CYP1B1CYP1A2ABCB1 | |
| SCHEMBL6175024 | 0.81 | CYSLTR1 (0.71) | CYSLTR1CYP1A1CYP1B1CYP1A2ABCB1 | |
| SCHEMBL6176758 | 0.80 | CYSLTR1 (0.75) | CYSLTR1 | |
| SCHEMBL6176722 | 0.79 | CYSLTR1 (0.57) | CYSLTR1CYP1A1CYP1B1CYP1A2ABCB1 | |
| SCHEMBL1516397 | 0.79 | CYSLTR1 (0.78) | CYSLTR1CYP1A1CYP1B1CYP1A2ABCB1 | |
| SCHEMBL10994445 | 0.78 | CYSLTR1 (0.78) | CYSLTR1CYP1A1CYP1B1CYP1A2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834510-B1 | Flavone derivative and medicine comprising the same | KOWA CO (JP) | 2005-02-23 | — | — | EP | disclosed |
| US-6136848-A | ANTIALLERGENS; ASTHMA THERAPY | KOWA CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0834510-A2 | Flavone derivative and medicine comprising the same | KOWA CO. LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |