Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAT1 | P18440 | 1/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 14/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.50 |
| ▸ | CLK1 | P49759 | 1/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.50 |
| ▸ | PIK3C2A | O00443 | 2/20 | 0.48 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | PRKDC | P78527 | 2/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.48 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.48 |
| ▸ | MYC | P01106 | 2/20 | 0.45 |
| ▸ | IL1RN | P18510 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174830 | 1.00 | NAT1 (0.55) | NAT1PIK3CGCSNK2A2CLK1CSNK2B | |
| SCHEMBL6173322 | 0.85 | CSNK2A2 (0.48) | PIK3CGCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL6173325 | 0.85 | CSNK2A2 (0.48) | PIK3CGCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL6185694 | 0.85 | CSNK2A2 (0.48) | PIK3CGCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL6842482 | 0.85 | CSNK2A2 (0.48) | PIK3CGCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL6173387 | 0.85 | PIK3CG (0.57) | PIK3CGCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL6173382 | 0.85 | PIK3CG (0.57) | PIK3CGCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL6176750 | 0.84 | CSNK2A2 (0.58) | NAT1PIK3CGCSNK2A2CLK1CSNK2B | |
| SCHEMBL6175239 | 0.84 | CSNK2A2 (0.58) | NAT1PIK3CGCSNK2A2CLK1CSNK2B | |
| SCHEMBL6840870 | 0.84 | CSNK2A2 (0.53) | NAT1PIK3CGCSNK2A2CLK1CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581529-A1 | BENZOXAZINES AND DERIVATIVES THEREOF AS INHIBITORS OF PI3KS | WARNER-LAMBERT COMPANY (US) | 2005-10-05 | — | — | EP | disclosed |
| US-20040138199-A1 | Benzoxazines and derivatives thereof as therapeutic agents | GOGLIOTTI ROCCO DEAN (US) | 2004-07-15 | — | — | US | disclosed |
| WO-2004056820-A1 | BENZOXAZINES AND DERIVATIVES THEREOF AS INHIBITORS OF PI3KS | WARNER-LAMBERT COMPANY LLC (US) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138199-A1 | Benzoxazines and derivatives thereof as therapeutic agents | XDH, TBXA2R, TBXAS1 | NAT1 2707/4885PIK3CG 4543/4885CSNK2A2 1130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.