Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175940 | 0.87 | ALDH1A1 (0.44) | ALDH1A1RAB9ASMN1; SMN2KDM4EPPARG | |
| SCHEMBL4951418 | 0.86 | ALDH1A1 (0.46) | ALDH1A1RAB9ASMN1; SMN2KDM4EPPARG | |
| SCHEMBL4948995 | 0.84 | ALDH1A1 (0.40) | ALDH1A1RAB9ASMN1; SMN2KDM4EPPARG | |
| SCHEMBL6173111 | 0.82 | ALDH1A1 (0.43) | ALDH1A1RAB9ASMN1; SMN2KDM4EPPARG | |
| SCHEMBL6252253 | 0.81 | NPSR1 (0.32) | NPSR1 | |
| SCHEMBL4951768 | 0.78 | ALDH1A1 (0.44) | ALDH1A1RAB9ASMN1; SMN2KDM4EPPARG | |
| SCHEMBL4951376 | 0.77 | ALDH1A1 (0.45) | ALDH1A1RAB9ASMN1; SMN2KDM4EPPARG | |
| SCHEMBL4955401 | 0.76 | ALDH1A1 (0.43) | ALDH1A1RAB9ASMN1; SMN2KDM4EPPARG | |
| SCHEMBL4949566 | 0.74 | ALDH1A1 (0.46) | ALDH1A1RAB9ASMN1; SMN2KDM4EPPARG | |
| SCHEMBL4949107 | 0.73 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2KDM4EHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567010-A1 | QUINOLIN-, ISOQUINOLIN-, AND QUINAZOLIN-OXYALKYLAMIDES AND THEIR USE AS FUNGICIDES | Syngenta Limited (GB) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004047538-A1 | QUINOLIN-, ISOQUINOLIN-, AND QUINAZOLIN-OXYALKYLAMIDES AND THEIR USE AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-06-10 | — | — | WO | disclosed |