Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.72 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.72 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 6/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16256981 | 0.90 | CARM1 (0.68) | CARM1PRMT6PABPC1DRD2CA12 | |
| SCHEMBL18741437 | 0.86 | KDM4E (0.68) | CARM1PRMT6PABPC1CA12CA1 | |
| SCHEMBL27944117 | 0.83 | CARM1 (0.68) | CARM1PRMT6PABPC1DRD2CA12 | |
| SCHEMBL916913 | 0.82 | CA12 (0.71) | CARM1PRMT6DRD2CA12CA1 | |
| SCHEMBL2674960 | 0.80 | POLB (0.68) | CARM1PRMT6CA12CA1CA2 | |
| SCHEMBL11932545 | 0.80 | CARM1 (0.63) | CARM1PRMT6CA12CA1CA2 | |
| SCHEMBL2575970 | 0.80 | CARM1 (0.59) | CARM1PRMT6CA12CA1CA2 | |
| SCHEMBL4500805 | 0.80 | PABPC1 (0.76) | CARM1PRMT6PABPC1DRD2KDM4E | |
| SCHEMBL7110809 | 0.80 | CARM1 (0.62) | CARM1PRMT6PABPC1DRD2CA12 | |
| SCHEMBL7500758 | 0.79 | CARM1 (0.62) | CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049676-B1 | 4- ARYL(PIPERIDIN-4-YL)] AMINOBENZAMIDES WHICH BIND TO THE DELTA-OPIOID RECEPTOR | ORTHO MCNEIL PHARM INC (US) | 2005-10-12 | — | — | EP | disclosed |
| US-6436959-B1 | DELTA-OPIOID RECEPTOR AGONISTS/ANTAGONISTS, ANALGESICS | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-08-20 | — | — | US | disclosed |
| EP-1049676-A1 | 4- ARYL(PIPERIDIN-4-YL)] AMINOBENZAMIDES WHICH BIND TO THE DELTA-OPIOID RECEPTOR | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999033806-A1 | 4-[ARYL(PIPERIDIN-4-YL)] AMINOBENZAMIDES WHICH BIND TO THE DELTA-OPIOID RECEPTOR | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 1999-07-08 | — | — | WO | disclosed |