Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.82 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.82 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL6176275 | 0.95 | OPRM1 (0.77) | OPRM1OPRD1OPRK1 | |
| Fumaric Acid SCHEMBL6176280 | 0.95 | OPRM1 (0.77) | OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL6171569 | 0.90 | OPRD1 (0.67) | OPRM1OPRD1OPRK1 | |
| SCHEMBL6173648 | 0.87 | OPRM1 (0.84) | OPRM1OPRD1OPRK1 | |
| SCHEMBL8145353 | 0.87 | OPRD1 (0.74) | OPRM1OPRD1OPRK1 | |
| SCHEMBL4499129 | 0.85 | OPRM1 (0.66) | OPRM1OPRD1OPRK1 | |
| SCHEMBL6329556 | 0.85 | OPRD1 (0.88) | OPRM1OPRD1OPRK1 | |
| SCHEMBL6336091 | 0.85 | OPRD1 (0.85) | OPRM1OPRD1OPRK1 | |
| SCHEMBL6334645 | 0.84 | OPRD1 (0.85) | OPRM1OPRD1OPRK1 | |
| SCHEMBL6332701 | 0.84 | OPRD1 (0.85) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049676-B1 | 4- ARYL(PIPERIDIN-4-YL)] AMINOBENZAMIDES WHICH BIND TO THE DELTA-OPIOID RECEPTOR | ORTHO MCNEIL PHARM INC (US) | 2005-10-12 | — | — | EP | disclosed |
| US-6436959-B1 | DELTA-OPIOID RECEPTOR AGONISTS/ANTAGONISTS, ANALGESICS | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-08-20 | — | — | US | disclosed |
| EP-1049676-A1 | 4- ARYL(PIPERIDIN-4-YL)] AMINOBENZAMIDES WHICH BIND TO THE DELTA-OPIOID RECEPTOR | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999033806-A1 | 4-[ARYL(PIPERIDIN-4-YL)] AMINOBENZAMIDES WHICH BIND TO THE DELTA-OPIOID RECEPTOR | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 1999-07-08 | — | — | WO | disclosed |