Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL552809 | 0.81 | TDP1 (0.38) | ALDH1A1TSHRTDP1CA1CA2 | |
| SCHEMBL27796400 | 0.80 | — | — | |
| SCHEMBL4887141 | 0.79 | EPHX1 (0.38) | ALDH1A1TSHRTDP1CA1CA12 | |
| SCHEMBL4887145 | 0.79 | EPHX1 (0.38) | ALDH1A1TSHRTDP1CA1CA12 | |
| SCHEMBL27859701 | 0.78 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL26363425 | 0.78 | CRBN (0.36) | ALDH1A1TSHRTDP1 | |
| SCHEMBL3342222 | 0.77 | TDP1 (0.46) | ALDH1A1TSHRTDP1CA1CA2 | |
| SCHEMBL8404812 | 0.77 | EPHX1 (0.38) | ALDH1A1TSHRTDP1CA1CA2 | |
| Butane SCHEMBL27501874 | 0.77 | CA1 (0.46) | ALDH1A1TDP1CTSDCA1CA2 | |
| SCHEMBL7819855 | 0.77 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2442107-B1 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | VENTANA MED SYST INC (US) | 2014-03-12 | — | — | EP | disclosed |
| EP-1142890-B1 | AMINOPYRAZOLE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2005-08-03 | — | — | EP | disclosed |
| US-6511997-B1 | For treatment of a disease associated with tumor necrosis factor alpha, interleukin 1, interleukin 6 or cyclooxygenase II; such as irritable bowel disease | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2003-01-28 | — | — | US | disclosed |
| EP-1142890-A1 | AMINOPYRAZOLE DERIVATIVES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |