Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | TNKS | O95271 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177248 | 0.88 | TNKS (0.66) | L3MBTL1TNKSMAPTNPC1RAB9A | |
| SCHEMBL10627793 | 0.85 | ABCG2 (0.58) | TNKSMAPTNPC1RAB9AKDM4E | |
| SCHEMBL31238530 | 0.85 | TNKS (0.66) | TNKSMAPTNPC1RAB9AKDM4E | |
| SCHEMBL1177191 | 0.83 | TNKS (0.74) | TNKSMAPTNPC1RAB9AKDM4E | |
| SCHEMBL11562626 | 0.82 | MAPT (0.72) | TNKSMAPTNPC1RAB9AKDM4E | |
| SCHEMBL11560525 | 0.81 | MAPT (0.53) | TNKSMAPTNPC1RAB9AKDM4E | |
| SCHEMBL10626539 | 0.81 | MAPT (0.73) | TNKSMAPTNPC1RAB9AKDM4E | |
| SCHEMBL11619136 | 0.81 | ABCG2 (0.64) | TNKSABCB1SIGMAR1BCHEABCG2 | |
| SCHEMBL28078087 | 0.78 | MAOB (0.67) | L3MBTL1TNKSMAPTNPC1RAB9A | |
| SCHEMBL6174522 | 0.78 | CYSLTR1 (0.73) | L3MBTL1MAPTABCB1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10109982-A | — | — | None | — | — | JP | disclosed |
| EP-0834510-B1 | Flavone derivative and medicine comprising the same | KOWA CO (JP) | 2005-02-23 | — | — | EP | disclosed |
| US-6136848-A | ANTIALLERGENS; ASTHMA THERAPY | KOWA CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| JP-H10109982-A | FLAVONE DERIVATIVE AND MEDICINE CONTAINING THE SAME | KOWA CO | 1998-04-28 | — | — | JP | disclosed |
| EP-0834510-A2 | Flavone derivative and medicine comprising the same | KOWA CO. LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |