Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272643 | 0.83 | — | — | |
| SCHEMBL31694894 | 0.78 | KDM4E (0.34) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL20701902 | 0.72 | — | — | |
| SCHEMBL25297626 | 0.72 | — | — | |
| SCHEMBL25248570 | 0.68 | — | — | |
| SCHEMBL23201305 | 0.68 | FFAR3 (0.34) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL11684096 | 0.65 | — | — | |
| SCHEMBL3628025 | 0.61 | ALDH1A1 (0.35) | ALDH1A1POLB | |
| SCHEMBL23858690 | 0.60 | KDM4E (0.33) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL23858688 | 0.60 | KDM4E (0.33) | KDM4EALDH1A1GLAPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513523-A1 | 1,5-DISUBSTITUTED IMIDAZOLIDIN-2-ONE DERIVATIVES FOR USE AS EP4 RECEPTOR AGONISTS IN THE TREATMENT OF EYE AND BONE DISEASES | Merck Frosst Canada & Co. (CA) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103664-A1 | 1,5-DISUBSTITUTED IMIDAZOLIDIN-2-ONE DERIVATIVES FOR USE AS EP4 RECEPTOR AGONISTS IN THE TREATMENT OF EYE AND BONE DISEASES | MERCK FROSST CANADA & CO. (CA) | 2003-12-18 | — | — | WO | disclosed |