Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL926627 | 0.79 | ALDH1A1 (0.34) | FFAR3ALDH1A1TSHR | |
| SCHEMBL631011 | 0.78 | BUB1 (0.35) | — | |
| SCHEMBL311298 | 0.78 | BUB1 (0.35) | — | |
| SCHEMBL1293778 | 0.78 | BUB1 (0.35) | — | |
| SCHEMBL31694898 | 0.78 | ALDH1A1 (0.44) | FFAR3ALDH1A1NOTUMNCOA1NCOA3 | |
| SCHEMBL1587391 | 0.78 | ALDH1A1 (0.44) | FFAR3ALDH1A1NOTUMNCOA1NCOA3 | |
| SCHEMBL15130399 | 0.78 | ALDH1A1 (0.44) | FFAR3ALDH1A1NOTUMNCOA1NCOA3 | |
| SCHEMBL23878341 | 0.73 | SMN1; SMN2 (0.38) | ALDH1A1TSHRKDM4EPOLB | |
| SCHEMBL20679760 | 0.73 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL8534149 | 0.73 | P2RX7 (0.47) | NCOA1NCOA3TSHRP2RX7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802489-A2 | MASP-2 INHIBITORS AND METHODS OF USE | Omeros Corporation (US) | 2021-04-14 | — | — | EP | disclosed |