Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 12/20 | 0.55 |
| ▸ | CCKAR | P32238 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6193345 | 0.90 | CCKBR (0.46) | CCKBRCCKARMAPTRAB9ANPC1 | |
| SCHEMBL6180953 | 0.85 | MAPT (0.47) | CCKBRCCKARMAPTRAB9ANPC1 | |
| SCHEMBL6178977 | 0.82 | CCKBR (0.57) | CCKBRCCKAR | |
| SCHEMBL6177552 | 0.80 | CCKBR (0.49) | CCKBRCCKARMAPT | |
| SCHEMBL6179633 | 0.79 | CCKBR (0.60) | CCKBR | |
| SCHEMBL6177891 | 0.79 | CCKBR (0.48) | CCKBRCCKAR | |
| SCHEMBL7960849 | 0.78 | CCKBR (0.47) | CCKBRCCKARRAB9A | |
| SCHEMBL6192779 | 0.77 | MAPT (0.39) | CCKBRCCKARMAPTRAB9ANPC1 | |
| SCHEMBL6178534 | 0.76 | CCKBR (0.48) | CCKBRCCKAR | |
| SCHEMBL6176858 | 0.76 | CCKBR (0.47) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945445-B9 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-0945445-B1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-0945445-A1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |