Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 10/20 | 0.47 |
| ▸ | CCKAR | P32238 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178675 | 0.89 | ACE (0.42) | CCKBRACEKMT2AL3MBTL1 | |
| SCHEMBL6178297 | 0.88 | CCKBR (0.43) | CCKBRCCKARACEKMT2AL3MBTL1 | |
| SCHEMBL6181104 | 0.88 | CCKBR (0.43) | CCKBRCCKARACEKMT2AL3MBTL1 | |
| SCHEMBL6181583 | 0.88 | CCKBR (0.43) | CCKBRCCKARACEKMT2AL3MBTL1 | |
| SCHEMBL6182762 | 0.87 | SCN9A (0.43) | CCKBRCCKARACEKMT2AL3MBTL1 | |
| SCHEMBL6177390 | 0.86 | CCKBR (0.45) | CCKBRACEKMT2AL3MBTL1 | |
| SCHEMBL15212822 | 0.84 | ACE (0.40) | CCKBRACEKMT2AL3MBTL1 | |
| SCHEMBL7466267 | 0.84 | CCKBR (0.52) | CCKBRCCKARRAB9AKMT2AMEN1 | |
| SCHEMBL6179669 | 0.84 | CCKBR (0.43) | CCKBRCCKARRAB9AACEKMT2A | |
| SCHEMBL6178646 | 0.83 | POLB (0.43) | CCKBRCCKARACEKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |