Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 2/20 | 0.57 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.53 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.53 |
| ▸ | TERT | O14746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8874138 | 0.91 | CYSLTR1 (0.59) | TNKSCYSLTR1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL6177272 | 0.90 | CYP1A1 (0.56) | TNKSCYSLTR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6176722 | 0.85 | CYSLTR1 (0.57) | TNKSCYSLTR1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL6176117 | 0.82 | CYSLTR1 (0.58) | TNKSCYSLTR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6178507 | 0.81 | CYSLTR1 (0.52) | TNKSCYSLTR1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL6177306 | 0.80 | CYSLTR1 (0.57) | TNKSCYSLTR1KDM4EMAOB | |
| SCHEMBL6175634 | 0.79 | CYSLTR1 (0.79) | CYSLTR1 | |
| SCHEMBL6178502 | 0.79 | CYSLTR1 (0.80) | TNKSCYSLTR1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL8875513 | 0.78 | CYP1A2 (0.49) | TNKSCYSLTR1TDP1CYP1A1CYP1A2 | |
| SCHEMBL6175933 | 0.77 | GABRP (0.56) | TNKSCYSLTR1CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834510-B1 | Flavone derivative and medicine comprising the same | KOWA CO (JP) | 2005-02-23 | — | — | EP | disclosed |
| US-6136848-A | ANTIALLERGENS; ASTHMA THERAPY | KOWA CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0834510-A2 | Flavone derivative and medicine comprising the same | KOWA CO. LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |