Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 20/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 17/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 13/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879325 | 0.92 | OPRD1 (0.85) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5879329 | 0.89 | OPRD1 (0.81) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6394863 | 0.87 | OPRD1 (0.88) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5879321 | 0.87 | OPRD1 (0.76) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5879405 | 0.85 | OPRD1 (0.78) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5879326 | 0.85 | OPRD1 (0.74) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6395295 | 0.85 | OPRD1 (0.74) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5879362 | 0.84 | OPRD1 (0.73) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5879365 | 0.84 | OPRD1 (0.73) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6865749 | 0.84 | OPRD1 (0.83) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395558-B1 | 4-(PHENYL-(PIPERIDIN-4-YL)-AMINO)-BENZAMIDE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PAIN, ANXIETY OR GASTROINTESTINAL DISORDERS | ASTRAZENECA AB (SE) | 2005-12-21 | — | — | EP | claimed |