Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174519 | 0.91 | CYSLTR1 (0.69) | CYSLTR1NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL6177251 | 0.84 | CYSLTR1 (0.81) | CYSLTR1CYSLTR2 | |
| SCHEMBL6174892 | 0.83 | CYSLTR1 (0.81) | CYSLTR1CYSLTR2 | |
| SCHEMBL6176265 | 0.83 | CYSLTR1 (0.58) | CYSLTR1NPC1RAB9ACYSLTR2 | |
| SCHEMBL6176271 | 0.82 | CYSLTR1 (0.61) | CYSLTR1 | |
| SCHEMBL6176136 | 0.79 | CYSLTR1 (0.82) | CYSLTR1CYSLTR2 | |
| SCHEMBL6175049 | 0.78 | CYSLTR1 (0.50) | CYSLTR1TP53SMN1; SMN2 | |
| SCHEMBL6175933 | 0.78 | GABRP (0.56) | CYSLTR1TP53SMN1; SMN2 | |
| SCHEMBL6176262 | 0.75 | CYSLTR1 (0.48) | CYSLTR1 | |
| SCHEMBL6175860 | 0.74 | CYSLTR1 (0.80) | CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834510-B1 | Flavone derivative and medicine comprising the same | KOWA CO (JP) | 2005-02-23 | — | — | EP | disclosed |
| US-6136848-A | ANTIALLERGENS; ASTHMA THERAPY | KOWA CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0834510-A2 | Flavone derivative and medicine comprising the same | KOWA CO. LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |