Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14635930 | 0.82 | KDM4E (0.48) | CSNK1A1TYRO3DYRK1BKDM4EALDH1A1 | |
| SCHEMBL6589526 | 0.81 | BCAT2 (0.49) | CSNK1A1TYRO3DYRK1BKDM4EALDH1A1 | |
| SCHEMBL31213435 | 0.77 | SLC6A2 (0.53) | KDM4EALDH1A1HPGDHSD17B10BCAT2 | |
| SCHEMBL168005 | 0.77 | SLC6A2 (0.53) | KDM4EALDH1A1HPGDHSD17B10BCAT2 | |
| SCHEMBL28700871 | 0.77 | KDM4E (0.48) | CSNK1A1TYRO3DYRK1BKDM4EALDH1A1 | |
| SCHEMBL3820615 | 0.75 | KDM4E (0.65) | CSNK1A1TYRO3DYRK1BKDM4EALDH1A1 | |
| SCHEMBL6174571 | 0.74 | MAPT (0.55) | CSNK1A1TYRO3DYRK1BKDM4EALDH1A1 | |
| SCHEMBL6178960 | 0.74 | KMT2A (0.48) | TRPV1CSNK1A1TYRO3DYRK1BALDH1A1 | |
| SCHEMBL6174457 | 0.71 | KDM4E (0.61) | TRPV1CSNK1A1TYRO3DYRK1BKDM4E | |
| SCHEMBL2330384 | 0.71 | KMT2A (0.50) | CSNK1A1TYRO3DYRK1BKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575918-A2 | SUBSTITUTED BIARYL-4-CARBOXYLIC ACID ARYLAMIDE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2005-09-21 | — | — | EP | claimed |
| WO-2004056774-A2 | SUBSTITUTED BIPHENYL-4-CARBOXYLIC ACID ARYLAMIDE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2004-07-08 | — | — | WO | claimed |