Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29740080 | 0.90 | KMT2A (0.48) | KMT2AMEN1HSD17B10TRPV1TSHR | |
| SCHEMBL28002534 | 0.79 | KMT2A (0.66) | KMT2AMEN1HSD17B10TSHRL3MBTL1 | |
| Hydrochloric Acid SCHEMBL30006002 | 0.77 | KMT2A (0.64) | KMT2AMEN1HSD17B10TSHRL3MBTL1 | |
| Hydrochloric Acid SCHEMBL30004917 | 0.77 | KMT2A (0.64) | KMT2AMEN1HSD17B10TSHRL3MBTL1 | |
| SCHEMBL29686594 | 0.77 | SMN1; SMN2 (0.58) | KMT2AMEN1HSD17B10TSHRL3MBTL1 | |
| SCHEMBL6176903 | 0.74 | TRPV1 (0.43) | HSD17B10TRPV1CSNK1A1TYRO3DYRK1B | |
| SCHEMBL3820615 | 0.73 | KDM4E (0.65) | TSHRCSNK1A1TYRO3DYRK1BL3MBTL1 | |
| SCHEMBL6178956 | 0.72 | ALDH1A1 (0.43) | KMT2AMEN1HSD17B10CSNK1A1TYRO3 | |
| SCHEMBL6174571 | 0.72 | MAPT (0.55) | CSNK1A1TYRO3DYRK1BALDH1A1BCAT2 | |
| SCHEMBL6175956 | 0.71 | TRPV1 (0.47) | HSD17B10TRPV1CSNK1A1TYRO3DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575918-A2 | SUBSTITUTED BIARYL-4-CARBOXYLIC ACID ARYLAMIDE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2005-09-21 | — | — | EP | claimed |
| WO-2004056774-A2 | SUBSTITUTED BIPHENYL-4-CARBOXYLIC ACID ARYLAMIDE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2004-07-08 | — | — | WO | claimed |