Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7498912 | 0.83 | LTA4H (0.40) | FFAR1 | |
| SCHEMBL27557959 | 0.83 | PTPN1 (0.43) | GBA1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7496494 | 0.80 | MEN1 (0.41) | ENPP3ENPP1NPC1MEN1KMT2A | |
| SCHEMBL6177202 | 0.80 | CTSA (0.49) | ALOX5FFAR1LMNA | |
| SCHEMBL8505924 | 0.78 | LMNA (0.53) | RAB9ASMN1; SMN2L3MBTL1ALOX5LMNA | |
| SCHEMBL8505922 | 0.78 | LMNA (0.53) | RAB9ASMN1; SMN2L3MBTL1ALOX5LMNA | |
| SCHEMBL2844054 | 0.78 | LMNA (0.53) | RAB9ASMN1; SMN2L3MBTL1ALOX5LMNA | |
| SCHEMBL6179653 | 0.77 | MAPK9 (0.48) | NPC1RAB9AKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL27557957 | 0.76 | GBA1 (0.48) | GBA1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL1419820 | 0.76 | MEN1 (0.53) | NPC1RAB9AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061921-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2005-03-30 | — | — | EP | disclosed |
| EP-1061921-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-12-27 | — | — | EP | disclosed |
| WO-1999045927-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-09-16 | — | — | WO | disclosed |