Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358307 | 0.89 | LOXL2 (0.56) | LOXL2CYP1A2NCF1HTR1AADRA1D | |
| SCHEMBL5495469 | 0.86 | CYP19A1 (0.54) | LOXL2CYP3A4HIF1AKDM4ELMNA | |
| SCHEMBL334360 | 0.85 | LOXL2 (0.67) | LOXL2CYP1A2NCF1HTR1AADRA1D | |
| SCHEMBL31599195 | 0.85 | LOXL2 (0.67) | LOXL2CYP1A2NCF1HTR1AADRA1D | |
| Bromide SCHEMBL9399386 | 0.83 | LOXL2 (0.64) | LOXL2CYP1A2NCF1HTR1AADRA1D | |
| SCHEMBL2331919 | 0.82 | LOXL2 (0.62) | LOXL2CYP1A2NCF1HTR1AADRA1D | |
| SCHEMBL2333461 | 0.82 | LOXL2 (0.62) | LOXL2CYP1A2NCF1HTR1AADRA1D | |
| SCHEMBL6966651 | 0.80 | LOXL2 (0.60) | LOXL2CYP1A2NCF1HTR1AADRA1D | |
| SCHEMBL6223283 | 0.80 | LOXL2 (0.71) | LOXL2CYP1A2NCF1HTR1AADRA1D | |
| SCHEMBL7747842 | 0.80 | LOXL2 (0.60) | LOXL2CYP1A2NCF1HTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-111517902-B | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-111517902-A | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2020-08-11 | — | — | CN | disclosed |
| CN-109293551-A | Method and composition relevant to granulocyte colony stimulating factor receptor | 利亘制药公司 | 2019-02-01 | — | — | CN | disclosed |
| CN-107533297-A | Material for forming underlayer film for lithography, composition for forming underlayer film for lithography, and pattern formation method | 三菱瓦斯化学株式会社 | 2018-01-02 | — | — | CN | disclosed |
| CN-107430344-A | Lower layer film for lithography, which forms to be formed with material, lower layer film for lithography, uses composition, lower layer film for lithography and pattern formation method | 三菱瓦斯化学株式会社 | 2017-12-01 | — | — | CN | disclosed |
| CN-107405870-A | Layered product, temporary bond composition and temporary bond film | 富士胶片株式会社 | 2017-11-28 | — | — | CN | disclosed |
| CN-106575083-A | Underlayer film-forming composition for lithography, underlayer film for lithography, and pattern forming method | 三菱瓦斯化学株式会社 | 2017-04-19 | — | — | CN | disclosed |
| EP-1392280-A4 | ARYLSULFONAMIDE ETHERS, AND METHODS OF USE THEREOF | WARNER LAMBERT CO (US) | 2005-11-30 | — | — | EP | disclosed |
| US-6875765-B2 | Arylsulfonamide ethers, and methods of use thereof | WARNER-LAMBERT COMPANY (US) | 2005-04-05 | — | — | US | disclosed |
| EP-0975602-A1 | IMIDAZOLE AND IMIDAZOLINE DERIVATIVES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046572-A1 | IMIDAZOLE AND IMIDAZOLINE DERIVATIVES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1998-10-22 | — | — | WO | disclosed |
| US-5817822-A | ANTITUOR, ANTIINFLAMMATORY AND ANTIARTHRITIC AGENTS | NOVARTIS CORPORATION (US) | 1998-10-06 | — | — | US | disclosed |
| CN-1092769-A | Cyclic urea derivatives, the method that contains the pharmaceutical composition of these compounds and prepare them | THOMAE GMBH DR K (DE) | 1994-09-28 | — | — | CN | disclosed |
| US-4900839-A | SUBSTITUTED PHENYLPROPENAMIDES | PFIZER INC. (US) | 1990-02-13 | — | — | US | disclosed |
| US-4837334-A | Precursors to quinolone inotropic agents | PFIZER INC. (US) | 1989-06-06 | — | — | US | disclosed |
| US-4728653-A | CONGESTIVE HEART FAILURE | PFIZER INC. (US) | 1988-03-01 | — | — | US | disclosed |
| EP-0053964-B1 | 1(4-QUINOLYL)ETHANOL OR PROPANOL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | PHARMUKA LABORATOIRES (FR) | 1986-05-07 | — | — | EP | disclosed |
| EP-0166533-A1 | Quinolone inotropic agents | Pfizer Limited (GB) | 1986-01-02 | — | — | EP | disclosed |
| EP-0053964-A1 | 1(4-Quinolyl)ethanol or propanol derivatives, pharmaceutical compositions containing them and processes for their preparation | PHARMUKA LABORATOIRES (FR) | 1982-06-16 | — | — | EP | disclosed |