Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 9/20 | 0.66 |
| ▸ | HTR6 | P50406 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR1F | P30939 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | SGK1 | O00141 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177259 | 1.00 | UTS2R (0.66) | UTS2RHTR6ALDH1A1LMNAWDR5 | |
| SCHEMBL6672599 | 0.89 | UTS2R (0.66) | UTS2RHTR6 | |
| SCHEMBL8342125 | 0.87 | UTS2R (0.66) | UTS2RHTR6ALDH1A1LMNAHTR2C | |
| SCHEMBL6706961 | 0.86 | UTS2R (0.66) | UTS2RHTR6ALDH1A1LMNAHTR1A | |
| SCHEMBL5835483 | 0.85 | UTS2R (0.72) | UTS2RHTR6SGK1 | |
| SCHEMBL5835487 | 0.85 | UTS2R (0.72) | UTS2RHTR6SGK1 | |
| SCHEMBL6179408 | 0.84 | UTS2R (0.59) | UTS2RHTR6ALDH1A1LMNASGK1 | |
| SCHEMBL6750398 | 0.84 | UTS2R (0.59) | UTS2RHTR6ALDH1A1LMNASGK1 | |
| SCHEMBL5834957 | 0.84 | UTS2R (0.71) | UTS2RHTR6ALDH1A1LMNASGK1 | |
| SCHEMBL5834952 | 0.84 | UTS2R (0.71) | UTS2RHTR6ALDH1A1LMNASGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385841-A4 | SULFONAMIDES | SMITHKLINE BEECHAM CORP (US) | 2005-03-02 | — | — | EP | claimed |
| US-20040142948-A1 | Sulfonamides | DHANAK DASHYANT (US) | 2004-07-22 | — | — | US | claimed |
| EP-1385841-A1 | SULFONAMIDES | SmithKline Beecham Corporation (US) | 2004-02-04 | — | — | EP | claimed |
| WO-2002090353-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-11-14 | — | — | WO | claimed |
| EP-1385841-A4 | SULFONAMIDES | SMITHKLINE BEECHAM CORP (US) | 2005-03-02 | — | — | EP | disclosed |
| US-20040142948-A1 | Sulfonamides | DHANAK DASHYANT (US) | 2004-07-22 | — | — | US | disclosed |
| EP-1385841-A1 | SULFONAMIDES | SmithKline Beecham Corporation (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002090353-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142948-A1 | Sulfonamides | UTS2R, PRSS2, STS | UTS2R 1/4885HTR6 2239/4885ALDH1A1 3733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.