SCHEMBL6672599

SCHEMBL6672599

CN1CCC(Oc2cc(NS(=O)(=O)c3cccc4c(Cl)cccc34)ccc2C(F)(F)F)C1

nearest known ligand 0.66

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 16/20 0.66
HTR6 P50406 3/20 0.54
P2RY4 P51582 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8337677 0.90 UTS2R (0.67) UTS2RHTR6
SCHEMBL6676194 0.89 UTS2R (0.68) UTS2RHTR6
SCHEMBL6676187 0.89 UTS2R (0.68) UTS2RHTR6
SCHEMBL8337458 0.89 UTS2R (0.68) UTS2RHTR6
SCHEMBL6177259 0.89 UTS2R (0.66) UTS2RHTR6
SCHEMBL6177261 0.89 UTS2R (0.66) UTS2RHTR6
SCHEMBL6672873 0.88 UTS2R (0.64) UTS2RHTR6
SCHEMBL8338096 0.88 UTS2R (0.64) UTS2RHTR6
SCHEMBL6677101 0.88 UTS2R (0.64) UTS2RHTR6
SCHEMBL5835543 0.86 UTS2R (0.71) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043369-A2 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO claimed
WO-2004043369-A2 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO disclosed