Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.46 |
| ▸ | ITGAV | P06756 | 9/20 | 0.46 |
| ▸ | ITGB6 | P18564 | 4/20 | 0.46 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | SUCNR1 | Q9BXA5 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174342 | 0.78 | ITGB3 (0.45) | ITGB3ITGAVITGB6ITGB5ITGB1 | |
| SCHEMBL6179695 | 0.77 | ITGB3 (0.64) | ITGB3ITGAVITGB6ITGB5ITGB1 | |
| SCHEMBL6178117 | 0.77 | ITGB3 (0.64) | ITGB3ITGAVITGB6ITGB5ITGB1 | |
| SCHEMBL6178761 | 0.77 | ITGB3 (0.64) | ITGB3ITGAVITGB6ITGB5ITGB1 | |
| SCHEMBL7519784 | 0.72 | ITGB3 (0.61) | ITGB3ITGAVITGB6ITGB5ITGB1 | |
| SCHEMBL6178108 | 0.72 | ITGB3 (0.61) | ITGB3ITGAVITGB6ITGB5ITGB1 | |
| SCHEMBL7516361 | 0.69 | ITGB3 (0.64) | ITGB3ITGAVITGB6ITGB5ITGB1 | |
| SCHEMBL6178644 | 0.69 | ITGB3 (0.64) | ITGB3ITGAVITGB6ITGB5ITGB1 | |
| SCHEMBL6175350 | 0.66 | ITGB3 (0.59) | ITGB3ITGAVITGB6ITGB5ITGB1 | |
| SCHEMBL6179307 | 0.65 | ITGB3 (0.56) | ITGB3ITGAVITGB6ITGB5ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061921-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2005-03-30 | — | — | EP | disclosed |
| EP-1061921-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-12-27 | — | — | EP | disclosed |
| WO-1999045927-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-09-16 | — | — | WO | disclosed |