Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6179383 | 0.97 | DNM1 (0.48) | DNM1TSHRTHRBMEN1HTT | |
| SCHEMBL27471804 | 0.95 | DNM1 (0.48) | DNM1TSHRTHRBMEN1HTT | |
| SCHEMBL27822061 | 0.93 | DNM1 (0.47) | DNM1TSHRTHRBMEN1HTT | |
| SCHEMBL10586750 | 0.93 | DNM1 (0.47) | DNM1TSHRTHRBMEN1HTT | |
| SCHEMBL27475653 | 0.92 | DNM1 (0.45) | DNM1TSHRTHRBHTTLPAR1 | |
| SCHEMBL1527700 | 0.89 | ADRB2 (0.41) | DNM1TSHRTHRB | |
| SCHEMBL27508527 | 0.87 | DNM1 (0.42) | DNM1TSHRHTTLPAR1LPAR3 | |
| SCHEMBL28873662 | 0.86 | ADRB2 (0.39) | DNM1TSHRTHRB | |
| SCHEMBL27469429 | 0.84 | DNM1 (0.39) | DNM1HTTLPAR1LPAR3LPAR2 | |
| SCHEMBL27492913 | 0.84 | DNM1 (0.44) | DNM1TSHRTHRBLPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945445-B9 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-0945445-B1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-0945445-A1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |
| US-4097491-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |