Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175964 | 0.79 | KDM4E (0.36) | HPGDKDM4ELMNATSHR | |
| SCHEMBL4874738 | 0.75 | MEN1 (0.46) | MEN1KMT2AL3MBTL1HPGDKDM4E | |
| SCHEMBL7127097 | 0.75 | DRD2 (0.43) | ALDH1A1 | |
| SCHEMBL7128107 | 0.70 | CYP3A4 (0.39) | MEN1KMT2A | |
| SCHEMBL4874362 | 0.70 | KDM4E (0.44) | MEN1KMT2ATDP1L3MBTL1HPGD | |
| SCHEMBL4873844 | 0.70 | ALDH1A1 (0.38) | MEN1KMT2ATDP1L3MBTL1HPGD | |
| SCHEMBL4878132 | 0.70 | ALDH1A1 (0.34) | MEN1KMT2AHPGDKDM4EALDH1A1 | |
| SCHEMBL7124328 | 0.69 | DRD2 (0.47) | — | |
| SCHEMBL7125210 | 0.69 | HRH3 (0.32) | — | |
| SCHEMBL7118543 | 0.69 | HRH3 (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399438-B1 | NOVEL HETEROARYL DERIVATIVES, THEIR PREPARATION AND USE | LUNDBECK & CO AS H (DK) | 2005-12-07 | — | — | EP | claimed |