Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27799366 | 0.86 | DYRK1A (0.58) | DYRK1AEGLN2GRM4KMOHDAC6 | |
| SCHEMBL16385221 | 0.84 | NPC1 (0.45) | DYRK1AGRM4KDM4EALDH1A1HPGD | |
| SCHEMBL30980806 | 0.82 | DYRK1A (0.41) | DYRK1ARIPK2SYKKDM4EALDH1A1 | |
| SCHEMBL30980827 | 0.81 | SLC6A4 (0.42) | DYRK1AALDH1A1MEN1KMT2A | |
| SCHEMBL21289970 | 0.77 | DYRK1A (0.55) | DYRK1AEGLN2GRM4KMOHDAC6 | |
| SCHEMBL27799325 | 0.77 | DYRK1A (0.58) | DYRK1AEGLN2GRM4KMOHDAC6 | |
| SCHEMBL4302847 | 0.76 | DYRK1A (0.65) | DYRK1AEGLN2KMORIPK2CHEK1 | |
| SCHEMBL7604725 | 0.75 | DYRK1A (0.56) | DYRK1AEGLN2KMORIPK2KDM4C | |
| SCHEMBL2657440 | 0.74 | BRD4 (0.40) | DYRK1AKDM4EALDH1A1G6PD | |
| SCHEMBL23012155 | 0.74 | RIPK2 (0.53) | DYRK1AEGLN2GRM4KMOHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708756-B1 | SUBSTITUTED 2-PHENYLPYRIDINES WITH HERBICIDAL ACTION | BASF AG (DE) | 2005-06-01 | — | — | EP | disclosed |
| US-5783522-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-07-21 | — | — | US | disclosed |
| EP-0708756-A1 | SUBSTITUTED 2-PHENYLPYRIDINES WITH HERBICIDAL ACTION | BASF AKTIENGESELLSCHAFT (DE) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002580-A2 | SUBSTITUTED 2-PHENYLPYRIDINES WITH HERBICIDAL ACTION | BASF AKTIENGESELLSCHAFT (DE) | 1995-01-26 | — | — | WO | disclosed |