SCHEMBL27799366

SCHEMBL27799366

COc1cc(-c2ncccc2N)ccc1Cl

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.58
G6PD P11413 1/20 0.47
RIPK2 O43353 1/20 0.44
EGLN2 Q96KS0 1/20 0.44
ALDH1A1 P00352 1/20 0.42
CYP3A4 P08684 1/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
GRM4 Q14833 2/20 0.42
KMO O15229 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
GAA P10253 1/20 0.41
NPC1 O15118 1/20 0.41
KDM4C Q9H3R0 2/20 0.40
NSD2 O96028 1/20 0.40
CASP6 P55212 1/20 0.40
KDM5A P29375 1/20 0.40
KDM5B Q9UGL1 1/20 0.40
SYK P43405 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4867570 0.86 L3MBTL1 (0.49) G6PDALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL6178667 0.86 DYRK1A (0.55) DYRK1AG6PDRIPK2EGLN2ALDH1A1
SCHEMBL16385223 0.81 SRC (0.45) G6PDALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL28417539 0.80 SYK (0.55) SYKADORA2AADORA1
SCHEMBL5918086 0.80 MAPT (0.51) ALDH1A1HSD17B10GAANPC1SYK
SCHEMBL27799325 0.79 DYRK1A (0.58) DYRK1AG6PDEGLN2GRM4KMO
SCHEMBL1786159 0.77 KDM4E (0.44) ALDH1A1HSD17B10GAANPC1
SCHEMBL5918047 0.76 MAOB (0.56) ALDH1A1ADORA1
SCHEMBL7604725 0.75 DYRK1A (0.56) DYRK1ARIPK2EGLN2ALDH1A1CYP3A4
SCHEMBL1551352 0.74 KDM4E (0.65) DYRK1AALDH1A1TDP1NPC1SYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101939296-A Carbazole-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORP 2011-01-05 CN disclosed