Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 4/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.49 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.49 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177903 | 0.89 | KCNQ3 (0.52) | KCNQ3KCNQ2KCNE1KCNQ1GAA | |
| Hydrochloric Acid SCHEMBL6179651 | 0.88 | KCNQ3 (0.51) | KCNQ3KCNQ2KCNE1KCNQ1GAA | |
| SCHEMBL6179205 | 0.88 | RAB9A (0.57) | KCNQ3KCNQ2KCNE1KCNQ1GAA | |
| SCHEMBL6180396 | 0.86 | GRM8 (0.45) | GAAGRM8GRM7GRM4RAB9A | |
| SCHEMBL6176251 | 0.86 | NPC1 (0.47) | KCNQ3KCNQ2KCNE1KCNQ1GAA | |
| SCHEMBL6180980 | 0.84 | NPC1 (0.45) | KCNQ3KCNQ2KCNE1KCNQ1GAA | |
| SCHEMBL6178473 | 0.84 | RAB9A (0.53) | KCNQ3KCNQ2KCNE1KCNQ1GAA | |
| SCHEMBL6178259 | 0.84 | KCNQ3 (0.50) | KCNQ3KCNQ2KCNE1KCNQ1GAA | |
| SCHEMBL6178924 | 0.81 | RAB9A (0.46) | KCNQ3KCNQ2KCNE1KCNQ1P4HTM | |
| SCHEMBL28346688 | 0.80 | NPC1 (0.48) | KCNQ3KCNQ2RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066261-B1 | PYRIDINE DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME | OTSUKA PHARMA CO LTD (JP) | 2005-11-23 | — | — | EP | disclosed |
| US-6511995-B1 | Inhibits collagen synthesis, which is useful for prophylaxis or treatment of fibrosis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-28 | — | — | US | disclosed |