Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.51 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 5/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6616895 | 0.80 | PARP1 (0.50) | NPC1KDM4EALDH1A1GAAPARP1 | |
| SCHEMBL3100405 | 0.80 | NPC1 (0.50) | NPC1KDM4EPARP1GRM5PLAU | |
| SCHEMBL30039613 | 0.80 | CSNK1A1 (0.49) | BCAT2ALOX5APFEN1PARP1CSNK1A1 | |
| SCHEMBL28271036 | 0.78 | NPC1 (0.74) | NPC1KDM4EPLAURAB9AL3MBTL1 | |
| SCHEMBL6028762 | 0.76 | BTK (0.47) | KDM4EALDH1A1GAAPARP1CSNK1A1 | |
| SCHEMBL995473 | 0.75 | PARP1 (0.54) | NPC1BCAT2PARP1RAB9AIKBKB | |
| SCHEMBL31127659 | 0.75 | PARP1 (0.54) | NPC1BCAT2PARP1RAB9AIKBKB | |
| SCHEMBL31621280 | 0.75 | SLC6A2 (0.64) | NPC1BCAT2ALOX5APFEN1KDM4E | |
| SCHEMBL31621279 | 0.75 | SLC6A2 (0.64) | NPC1BCAT2ALOX5APFEN1KDM4E | |
| SCHEMBL2656924 | 0.74 | BCAT2 (0.51) | NPC1BCAT2ALOX5APFEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594841-A1 | VEGFR-2 AND VEGFR-3 INHIBITORY ANTHRANYLAMIDOPYRIDINES | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004013102-A1 | VEGFR-2 AND VEGFR-3 INHIBITORY ANTHRANYLAMIDOPYRIDINES | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-02-12 | — | — | WO | disclosed |